Is stopping THM responsible or not of a decrease in the incidence of cancer breast?

Authors

  • Henri ROZENBAUM

DOI:

https://doi.org/10.54695/rhh.26.01.4259

Keywords:

Hormone replacement therapy, Breast cancer, Estrogen, Progestogens, Mammography.

Abstract

Does stopping hormone replacement therapy account for a reduction in the incidence of breast cancer or not?
The publication of the results of the WHI study in
2002 led 50% of women to give up taking hormone
therapy for the menopause.
Over the years that followed, a reduction in the incidence of breast cancer was observed in most countries of the world. As hormone replacement therapy
(HRT) leads to a slight increase in the risk of breast
cancer (RR of around 1.3) it seems logical to observe
a reduction in the incidence of breast cancer after
stopping this treatment.
Other factors, however, seem to have also played a
rôle, and it is possible that the interruption of HRT
only accounts for 50% of the decrease in incidence
noted. The speed of this phenomenon along with the
fact that certain authors have noted a recent slight
increase in the incidence of breast cancer suggests a
promoting effect of HRT on these tumours.

Published

2013-03-01

Issue

Section

Articles